Attune Neurosciences is developing the world's first wearable, non-invasive ultrasound system for deep brain therapy. Our technology uses MRI-guided precision and adaptive stimulation to reach deep brain structures that no other non-invasive device can access, opening up new treatment options for patients with chronic pain, sleep disorders, and many other neurological and psychiatric conditions. We are headquartered in San Francisco, CA, venture-backed, and supported by grants from the National Institutes of Health and the Department of Defense. Our team includes scientists, engineers, and clinicians who are serious about delivering this technology to help patients in need.
In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form (Form I-9) upon hire.
Role
We are looking to hire a Clinical Research Manager to help develop, shape, and grow our clinical research program. We are looking for a proven leader with a project management mindset, hands-on experience in clinical trials, and the ability to consistently deliver results on tight timelines. This person will collaborate closely with our software team, study operators, and study leadership to ensure the smooth execution of multiple concurrent studies, and will provide operational leadership to a team of research associates by dynamically allocating their effort across studies as needs evolve.
This role is responsible for strategic planning to meet study goals and ensuring all milestones are met, including recruitment targets, data entry timelines, budget management, and device requirements, while keeping all studies in regulatory compliance. A strong command of IRB preparation and submission is essential, as this person will own the end-to-end process for applications, amendments, and renewals across studies. The success of the team depends on this individual's ability to manage performance, maintain morale, and uphold consistency in workload distribution across studies. The Clinical Research Manager will work closely with staff to identify gaps in training and process, bring experience translating protocols into actionable workflows, and must be comfortable stepping in for study visits when coverage is needed.
Compensation: $120,000 to $130,000 base salary, plus benefits and stock options. Title and compensation are based on experience. We conduct regular performance reviews, and compensation can grow rapidly for individuals who demonstrate strong impact. Attune is growing quickly and this role has a clear path upward in our Clinical Research organization.
Essential Responsibilities
- Timeline & Milestone Management: Keep multiple concurrent studies on track against timelines and enrollment targets. Proactively identify risks and develop mitigation strategies, and ensure all reporting milestones including recruitment, data entry, budget, and device requirements are met.
- Regulatory Compliance & IRB Management: Ensure all studies remain in compliance with IRB approvals, FDA regulations, and GCP guidelines. Prepare and submit IRB applications, amendments, renewals, and adverse event reports, and maintain audit-ready regulatory documentation.
- Team Supervision & Effort Allocation: Directly supervise a team of research associates. Dynamically allocate effort across studies based on phase and demand. Provide regular coaching, structured performance feedback, and day-to-day guidance to develop the team and maintain high standards.
- Protocol Translation & SOP Development: Translate research protocols into clearly documented, actionable workflows and SOPs. Identify gaps in team knowledge and ensure staff are trained, refreshed, and consistently adhering to procedures.
- Technology Fluency & Study Visit Support: Maintain hands-on fluency with the smartphone applications and wearable sensor systems used in our studies. Troubleshoot data collection issues, liaise with the software team on technical concerns, and step in to support study visits when needed.
- Data Quality Oversight: Oversee data quality review across studies. Ensure research associates are collecting, entering, and flagging data correctly, and work with study leadership to address inconsistencies promptly.
- Patient Safety Monitoring: Serve as the operational point of contact for study safety monitoring. Ensure adverse events and protocol deviations are identified, documented, and escalated appropriately.
This position is fully on-site, 5 days a week at our San Francisco office.
Minimum Qualifications
- Bachelor's degree in a relevant field such as clinical research, neuroscience, psychology, public health, biology, or a related life science discipline.
- At least 2 years of experience working in clinical research, with demonstrated involvement in study operations, regulatory compliance, or participant-facing research activities.
- Experience preparing IRB submissions and maintaining regulatory compliance tracking systems across multiple concurrent studies.
- Demonstrated ability to translate research protocols into clear, step-by-step workflows and SOPs that a research team can execute reliably.
- Experience supervising, mentoring, or providing structured performance feedback to junior staff or research team members.
- Comfortable with smartphone-based applications and wearable or biosensor data collection in a research context; able to troubleshoot basic technical issues and serve as a resource for the team.
- Strong organizational skills with the ability to manage multiple studies simultaneously and prioritize effectively under competing demands.
- Excellent verbal and written communication skills, including the ability to work fluidly across clinical, technical, and leadership stakeholders.
Preferred Qualifications
- Master's degree or advanced training in clinical research, public health, neuroscience, or a related field.
- 3 or more years of clinical research experience, including at least 1 year in a supervisory or team lead capacity.
- Hands-on experience with REDCap, eClinicalWorks, or other electronic data capture and clinical database platforms.
- Background working with psychiatric or neurological patient populations in a research or clinical setting.
- Familiarity with FDA regulations governing clinical investigations, GCP certification, or equivalent training.
- Experience collaborating with software or engineering teams on technology-driven research studies, including mobile health applications or sensor-based data collection.
- Bilingual candidates are strongly encouraged to apply.
Attune is an Equal Employment Opportunity Employer. We provide equal employment opportunities to all qualified applicants and employees, and prohibit discrimination and harassment of any type, without regard to race, sex, pregnancy, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, genetic information or any other status protected under federal, state, or local applicable laws. We will consider employment for qualified applicants with arrest and conviction records in accordance with fair chance laws.
